American Oil Beetles - Poisonous Blister Beetles
Do not ever touch these beetles! Bizarre bugs indeed! I happened upon about a dozen of these beauties in a fall mating frenzy centered around two very large females full of eggs. Fortunately I did not step on them in the middle of the trail. They are called Blister Beetles because they emit an oil that will burn the skin if you pick them up. The poison they contain is among the strongest known. Cantharidin is an odorless, colorless fatty substance of the terpenoid class, which is secreted by many species of blister beetles. It is a burn agent or a poison in large doses, but preparations containing it were historically used as aphrodisiacs. In its natural form, cantharidin is secreted by the male blister beetle and given to the female as a copulatory gift during mating. Afterwards, the female beetle covers her eggs with it as a defense against predators.
Poisoning from cantharidin is a significant veterinary concern, especially in horses, but it can also be poisonous to humans if taken internally (where the source is usually experimental self-exposure). Externally, cantharidin is a potent vesicant (blistering agent), exposure to which can cause severe chemical burns. Properly dosed and applied, the same properties have also been used therapeutically, for instance for treatment of skin conditions such as molluscum contagiosum infection of the skin.
Cantharidin is classified as an extremely hazardous substance in the United States, and is subject to strict reporting requirements by facilities which produce, store, or use it in significant quantities. This excerpt is from a great Blog post on these beetles at: https://thesmallermajority.com/2012/1...
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American Oil Beetles - Poisonous Blister Beetles
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